diff --git a/src/Ryujinx.Graphics.Gpu/Engine/Threed/StateUpdater.cs b/src/Ryujinx.Graphics.Gpu/Engine/Threed/StateUpdater.cs
index 6b4ea89f39..b3eb62185a 100644
--- a/src/Ryujinx.Graphics.Gpu/Engine/Threed/StateUpdater.cs
+++ b/src/Ryujinx.Graphics.Gpu/Engine/Threed/StateUpdater.cs
@@ -343,11 +343,22 @@ namespace Ryujinx.Graphics.Gpu.Engine.Threed
 
             bool unalignedChanged = _currentSpecState.SetHasUnalignedStorageBuffer(_channel.BufferManager.HasUnalignedStorageBuffers);
 
-            if (!_channel.TextureManager.CommitGraphicsBindings(_shaderSpecState) || unalignedChanged)
+            bool scaleMismatch;
+            do
             {
-                // Shader must be reloaded. _vtgWritesRtLayer should not change.
-                UpdateShaderState();
+                if (!_channel.TextureManager.CommitGraphicsBindings(_shaderSpecState, out scaleMismatch) || unalignedChanged)
+                {
+                    // Shader must be reloaded. _vtgWritesRtLayer should not change.
+                    UpdateShaderState();
+                }
+
+                if (scaleMismatch)
+                {
+                    // Binding textures changed scale of the bound render targets, correct the render target scale and rebind.
+                    UpdateRenderTargetState();
+                }
             }
+            while (scaleMismatch);
 
             _channel.BufferManager.CommitGraphicsBindings(_drawState.DrawIndexed);
         }
diff --git a/src/Ryujinx.Graphics.Gpu/Image/TextureManager.cs b/src/Ryujinx.Graphics.Gpu/Image/TextureManager.cs
index 3bf0beefdb..8c2a887271 100644
--- a/src/Ryujinx.Graphics.Gpu/Image/TextureManager.cs
+++ b/src/Ryujinx.Graphics.Gpu/Image/TextureManager.cs
@@ -360,15 +360,16 @@ namespace Ryujinx.Graphics.Gpu.Image
         /// Commits bindings on the graphics pipeline.
         /// </summary>
         /// <param name="specState">Specialization state for the bound shader</param>
+        /// <param name="scaleMismatch">True if there is a scale mismatch in the render targets, indicating they must be re-evaluated</param>
         /// <returns>True if all bound textures match the current shader specialization state, false otherwise</returns>
-        public bool CommitGraphicsBindings(ShaderSpecializationState specState)
+        public bool CommitGraphicsBindings(ShaderSpecializationState specState, out bool scaleMismatch)
         {
             _texturePoolCache.Tick();
             _samplerPoolCache.Tick();
 
             bool result = _gpBindingsManager.CommitBindings(specState);
 
-            UpdateRenderTargets();
+            scaleMismatch = UpdateRenderTargets();
 
             return result;
         }
@@ -426,9 +427,12 @@ namespace Ryujinx.Graphics.Gpu.Image
         /// <summary>
         /// Update host framebuffer attachments based on currently bound render target buffers.
         /// </summary>
-        public void UpdateRenderTargets()
+        /// <returns>True if there is a scale mismatch in the render targets, indicating they must be re-evaluated</returns>
+        public bool UpdateRenderTargets()
         {
             bool anyChanged = false;
+            float expectedScale = RenderTargetScale;
+            bool scaleMismatch = false;
 
             Texture dsTexture = _rtDepthStencil;
             ITexture hostDsTexture = null;
@@ -448,6 +452,11 @@ namespace Ryujinx.Graphics.Gpu.Image
             {
                 _rtHostDs = hostDsTexture;
                 anyChanged = true;
+
+                if (dsTexture != null && dsTexture.ScaleFactor != expectedScale)
+                {
+                    scaleMismatch = true;
+                }
             }
 
             for (int index = 0; index < _rtColors.Length; index++)
@@ -470,6 +479,11 @@ namespace Ryujinx.Graphics.Gpu.Image
                 {
                     _rtHostColors[index] = hostTexture;
                     anyChanged = true;
+
+                    if (texture != null && texture.ScaleFactor != expectedScale)
+                    {
+                        scaleMismatch = true;
+                    }
                 }
             }
 
@@ -477,6 +491,8 @@ namespace Ryujinx.Graphics.Gpu.Image
             {
                 _context.Renderer.Pipeline.SetRenderTargets(_rtHostColors, _rtHostDs);
             }
+
+            return scaleMismatch;
         }
 
         /// <summary>